clinically sharp ochagovaja a dystrophy. The important diagnostic value

you in section: clinically sharp ochagovaja a dystrophy

Through 3-5 ch after development ochagovoj myocardium dystrophies probably short-term (within 1-2 days) increase of activity of enzyme kreatinfosfokinazy (KFK), katalizirujushchego reaction fosforilirovanija kreatina in muscles; it is caused by the raised permeability of cellular membranes, delay of processes inaktivatsii and allocation of enzyme from blood.

The Important diagnostic value has definition in whey of blood KFK and its isoenzymes - ' MM ', ' MB ' and ' VV '. Especially authentic sign of damage of a myocardium is occurrence in blood izoenzima KFK - ' MB ' which is inherent only in myocardium cages. diagnostic value of detection ' MV '-fractions speaks that its activity raises earlier (in the first 1-3 ch diseases), than activity of the general KFK. Isoenzyme ' VV ' makes only 0,5% of the general KFK and it is found out in blood at damage of cages of a myocardium seldom. Isoenzyme ' MM ' except a myocardium contains and in skeletal muscles, its detection has no such value for diagnostics, as ' MB '.

Short-term increase in blood through 8-10 ch enzyme laktatdegidro-genazy (LDG), katalizirujushchego reversible reaction of transformation of dairy acid in pirovinogradnuju can be the Sign of damage of a myocardium also. More valuably for diagnostics detection ' warm ' its fractions - LDG, and ЛДГ2 which maintenance glozhet to raise already during the first hours diseases and to remain raised longer (till 1-3 days), than the general LDG.